Choosing the best probiotic for your needs

What do your intestines, brain, immune system, and urinary tract have in common? They all rely on a well-balanced microbiome of beneficial bacteria and yeast to stay healthy. The challenge is that this balance can easily be disrupted by stress, antibiotics, illness, a poor diet, and age-related declines.[1]

Probiotic supplements play an important role in re-establishing a healthy gut microflora and can provide extra support when you have specific health concerns. Although digestive health is one of the most common reasons for taking probiotics, they can also provide targeted support for low immunity, infections, gastrointestinal problems, and nutritional health.[2]

Just like the other nutrients in your food and supplements, different strains of probiotic bacteria and yeast have different functions in the body. To choose the right probiotic formula for your needs, consider which strains are best suited for your age, health, and lifestyle. Natural Factors’ line of probiotic supplements are condition specific. This makes it easier to choose the most effective combination of probiotic strains for your personal needs.

Ultimate Multi Probiotic

Ultimate Multi Probiotic is a 12-strain formula featuring a synergistic combination of Lactobacillus and Bifidobacterium strains from human, plant, and dairy sources. The strains are able to resist gastric acid, allowing them to reach the intestinal tract intact. This fantastic all-purpose probiotic supports the small and large intestines, as well as the gut-brain axis through which the gut microflora and brain communicate and harmonize gut and mental health.[3,4], It is guaranteed to contain 12 billion live probiotic cultures per vegetarian capsule at the time of expiry. For a convenient one-per-day dose of 24 billion live probiotic cultures, choose the double-strength formula.

Who should choose this?

Ultimate Multi Probiotic is formulated for adults who:

  • Want high-potency gastrointestinal support
  • Have food sensitivities
  • Suffer from gas, bloating, and abdominal pain
  • Want to support immune function
  • Are taking antibiotics


Women’s Multi Probiotic

Women’s Multi Probiotic combines 10 probiotic strains shown to support intestinal, vaginal, and urinary tract health. It features CranRich®, a cranberry 36:1 concentrate, to help prevent recurrent urinary tract infections (UTIs).[5] It also contains carefully selected, acid-resistant probiotic species, including L. fermentum and S. thermophilus, based on their success in published clinical studies on intestinal and vaginal flora.[6,7]

Who should choose this?

Women’s Multi Probiotic is formulated for women who:

  • Suffer from recurrent urinary tract infections
  • Are on antibiotics and want to restore a beneficial microflora
  • Want an all-in-one cranberry and probiotic formula to prevent UTIs


Critical Care Probiotic

Critical Care Probiotic contains nine Bifidobacterium and Lactobacillus strains for acute targeted support of both the small and large intestines. It is used to restore beneficial bacteria lost through antibiotic use and to enhance immune health. This formula offers significant protection

from antibiotic-associated bacterial infection, yeast overgrowth, and digestive discomfort.[8,9] Each strain in this formulation has been carefully selected for its natural resistance to gastric acid, allowing the probiotics to reach the intestines at full potency. It is available in concentrations of 55 billion and 100 billion live active cultures per vegetarian capsule for maximum support.

Who should choose this?

Critical Care Probiotic is formulated for people who are:

  • Taking antibiotics or suffering from antibiotic-associated gastrointestinal distress
  • At risk of yeast overgrowth, vaginal, or urinary tract infections
  • Diagnosed with Crohn’s disease, IBS, or other inflammatory bowel conditions
  • Concerned about their immune health or traveller’s diarrhea



Mega Probiotic

Mega Probiotic is a four-strain probiotic powder that can be added to food and drinks to help establish and maintain normal intestinal health. Each serving is guaranteed to contain 12 billion live active cells from Lactobacillus and Bifidobacterium strains, in addition to fructooligosaccharides (FOS) as a prebiotic to encourage probiotic growth and colonization.[10]

Who should choose this?

Mega Probiotic is a great choice for people who:

  • Do not like to take probiotics as capsules or pill formats
  • Want to restore intestinal health disrupted by antibiotics
  • Are interested in supporting a healthy intestinal flora

Calm Biotic®

Calm Biotic features Lactobacillus helveticus R0052 and Bifidobacterium longum R0175, two proprietary strains shown to reduce symptoms of stress and promote a healthy mood balance.[11] Both strains are resistant to gastric acid and can be used to help relieve stress-related gastrointestinal complications such as nausea and abdominal pain.[12] This formula is also shelf-stable, meaning no refrigeration is required!

Who should choose this?

Calm Biotic is formulated for people who:

  • Need extra support during times of stress, such as academic exams and sports competitions
  • Want to boost their mood during occasional stress
  • Suffer from gastrointestinal issues related to stress


IBS Relief Biotic®

IBS Relief Biotic is a multi-strain formula featuring Lactobacillus, Bacillus, and Enterococcus strains that are clinically tested and effective in relieving some symptoms of irritable bowel syndrome (IBS).[13] Each vegetarian capsule contains 7 billion live probiotic cultures to help reduce the risk of antibiotic-associated diarrhea and may help reduce the duration of diarrhea in people suffering from IBS.[14] It is also shelf stable, so no refrigeration is required!

Who should choose this?

IBS Relief Biotic is formulated for people who:

  • Suffer from IBS
  • Have gastrointestinal issues, poor digestion, or digestive upset
  • Want to support a healthy gut microbiome
  • Are dealing with age-related declines in intestinal microflora
  • Are on antibiotics and wish to protect and replenish friendly bacteria


Travel Biotic®

Travel Biotic BB536 is a high-potency probiotic with 10 billion live probiotic cultures of Bifidobacterium longum BB536 per capsule. BB536 is among the most researched and effective probiotics in the world. It promotes a favourable gut flora and supports a healthy immune system.[15] Travel Biotic is a one-per day formula that does not require refrigeration, making it convenient for travellers.

Who should choose this?

Travel Biotic BB536 is formulated for people who:

  • Want to promote gastrointestinal health while travelling
  • Are taking antibiotics
  • Have busy schedules and are often “on the go”

When it comes to maintaining and replenishing your microflora, a probiotic supplement will offer the most concentrated solution. To find the best probiotic formula for your needs, be sure to check the label to see which probiotic strain(s) it contains, the number of CFUs (colony forming units) per dose, and that it contains live or active cultures.



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[9] Klein A, Friedrich U, Vogelsang H, et al. Lactobacillus acidophilus 74-2 and Bifidobacterium animalis subsp lactis DGCC 420 modulate unspecific cellular immune response in healthy adults. Eur J Clin Nutr. 2008;62(5):584-93.
[10] Scholz-Ahrens KE, Ade P, Marten B, et al. Prebiotics, probiotics, and synbiotics affect mineral absorption, bone mineral content, and bone structure. J Nutr. 2007;137(3):838S-46S.
[11] Messaoudi M, Violle N, Bisson, JF, et al. Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers. Gut Microbes. 2011;2(4):256-61.
[12] Diop L, Guillou S, Durand H. Probiotic food supplement reduces stress-induced gastrointestinal symptoms in volunteers: a double-blind, placebo-controlled, randomized trial. Nutr Res. 2008;28(1):1-5.
[13] Foster LM, Tompkins TA, Dahl WJ. A comprehensive post-market review of studies on a probiotic product containing Lactobacillus helveticus R0052 and Lactobacillus rhamnosus R0011. Benef Microbes. 2011;2(4):319-34.
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[15] Wong CB, Odamaki, T, Xiao JZ. Beneficial effects of Bifidobacterium longum subsp. longum BB536 on human health: Modulation of gut microbiome as the principal action. J Funct Foods. 2019;54:506-19.