How to Get Your Groove Back

Are you running on fumes, depleted and exhausted? If so, you’re not alone. The past year and a half has been almost universally stressful and left a lot of us feeling that way.

Luckily, there are concrete steps you can take to lift your mood.

  • Get outside. Being outside, whether on a deserted beach, a quiet forest, or even your own backyard, connects us to nature and grounds us.
  • Exercise is a natural mood booster. Our bodies were meant to move, and they release feel-good endorphins when we do.
  • Call a friend. Sometimes a sympathetic ear is just what you need to feel lighter.
  • Eat healthy food. Vegetables, fruit, whole grains, lean meat, beans, and nuts give your brain what it needs to make happy chemicals.[1]


Saffron: A natural way to feel better*

Saffron, the crimson threads in the center of the Crocus sativus blossom, has been clinically shown to relieve occasional stress, improve mood, and encourage sleep.*[2,3,4,5,6]How does it work? Several ways.


Mood: Two active constituents of saffron, crocin and safranal, act on the feel-good neurotransmitters dopamine, norepinephrine, and serotonin in the brain.*[7]

Stress: Saffron also works on the hypothalamic pituitary adrenal (HPA) axis, which is responsible for the body’s stress response.*[8] Crocin and safranal are also antioxidants, which means they can help quench the extra free radicals your body produces when you’re under stress.*[9,10]

Sleep: Preliminary evidence suggests saffron balances the body’s histamine and cholinergic activities, thus encouraging non-REM sleep.*


Affron®: A better saffron


There’s just one catch: If you want to enjoy the health benefits of saffron, picking the right source is crucial. Saffron is the world’s most expensive spice and in high demand, so unsavory actors often sell adulterated products, passing fake saffron off as the real deal.

Affron is your answer. Affron is a 100% pure source of Spanish saffron extract that has been DNA-certified for authenticity and has undergone study in multiple clinical trials. It’s the saffron to use if you want to be sure what’s on the label is in the bottle. The company that makes Affron grows saffron sustainably in its own private fields in Spain and oversees the entire supply chain, working closely with farmers to ensure quality control.


What we love about Affron

There are a lot of things to love about Affron. First and foremost is the clinical research. Affron is the most clinically studied brand of saffron in the world, backed by eight human clinical trials. In adults and adolescents aged 12 and older, it has been shown to:

  • Improve mood and alleviate occasional stress*
  • Promote relaxation and restful sleep*
  • Produce significant results in as little as two weeks*

Second, Affron is standardized to contain 3.5% Lepticrosalides®, a complex of saffron’s active constituents (including crocin and safranal). That way, you know you’re getting the same level of activity from batch to batch and bottle to bottle.

Third, Affron is water-extracted with a patented process called AFF ON Cool-Tech® that preserves and concentrates the precious Lepticrosalides without the use of harsh chemicals. (Who needs those?) Because it’s concentrated, a small 28-mg is effective for mood and relaxation support.*

Is it any wonder Affron has won six international awards?


Stress-Relax® 100% Pure Saffron Extract

Natural Factors Stress-Relax 100% Pure Saffron Extract features Affron and no other active ingredients. It’s free from artificial colors, preservatives, sweeteners, dairy, starch, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, and GMOs and is suitable for vegans and vegetarians.

If life’s got you down (or stressed or sleepless), our 100% Pure Saffron Extract is your ticket to feeling better.*



[1] Does what you eat affect your mood? Cleveland Clinic. Jan. 12, 2021.

[2] Kell G, et al. affron® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial. Complement Ther Med. 2017 Aug;33:58-64.

[3] Lopresti AL, et al. J Psychopharmacol. 2019 Nov;33(11):1415-27.

[4] Lopresti AL, et al. J Affect Disord. 2018 May;232:349-57.

[5] Nishide A, et al. Sleep enhancement by saffron extract in randomized control trial. Japanese Pharmacol Therapeutics. 2018;46(8):1407-15.

[6] Lopresti AL, et al. J Clin Sleep Med. 2020;16(6):937-47.

[7] Siddiqui MJ, et al. J Pharm Bioallied Sci. 2018;10(4):173-80.

[8] Lopresti 2018.